综述视神经脊髓炎的白细胞抗原免疫遗传学
Humanleukocyteantigens-immunogeneticsofneuromyelitisopticaorDevicsdiseaseandtheimpactontheimmunopathogenesis,diagnosisandtreatment:acriticalreview
1DepartmentofNeurology,MedicalSchoolofNationalandKapodistrianUniversityofAthens,AeginitionHospital,Athens,Greece2DepartmentofNeurology;DepartmentofNeurology,ImmunogeneticsLaboratoryandDivisionofDemyelinatingDiseases,MedicalSchoolofNationalandKapodistrianUniversityofAthens,AeginitionHospital,Athens,Greece
CorrespondenceAddress:MariaPanosGontikaDepartmentofNeurology,ImmunogeneticsLaboratoryandDivisionofDemyelinatingDiseases,MedicalSchoolofNationalandKapodistrianUniversityofAthens,AeginitionHospital,VassilisisSofiasAvenue,AthensGreece
Abstract
Neuromyelitisoptica(NMO)isanautoimmunedemyelinatingdisorder,predominantlycharacterizedbysevereopticneuritis,transversemyelitisandthehighlevelofantibodiesagainstaquaporin-4(AQP4)orNMO-immunoglobulinG(IgG).ResearchestryingtocorrelateNMOwithspecifichumanleukocyteantigen(HLA)allelestookplaceinalimitedextendinthelastfewyears.Nevertheless,ithasbe北京哪家医院看白癜风专业口碑较好的白癜风医院
